Methylnaltrexone bromide
Metilnaltreksonijev bromid
new target medicine, its importance in palliative care
Keywords:
methylnaltrexone bromide, opioids, MNTX, opioid-induced constipationAbstract
No abstract.
Povzetek
Metilnaltreksonijev bromid (Relistor) je selektiven periferni antagonist vezave opioidov na receptorje. Uporablja se za zdravljenje zaprtja, ki je nastalo zaradi opioidov, kadar običajna odvajala niso učinkovita. MNTX ne vpliva na protibolečinski učinek opioidov. MNTX je novo tarčno zdravilo, ki ciljano blokira mehanizem z opioidi povzročenega zaprtja. Zaradi navedenih lastnosti omogoča optimalno obravnavo bolečine, ker odpravlja neobvladljivo zaprtje. Bolniku omogoča opravljanje vsakodnevnih dejavnosti in v zadnjem obdobju izboljša kakovost njegovega življenja. Neželeni učinki so manjši od dobrobiti (7). Zaradi navedenega so odgovorne ustanove odobrile MNTX za klinično uporabo
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Published
2008-12-15
Issue
Section
Review Article
License
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How to Cite
Methylnaltrexone bromide: new target medicine, its importance in palliative care. (2008). Onkologija, 12(2), 135-136. https://revijaonkologija.si/Onkologija/article/view/387
