Adjuvantno zdravljenje raka debelega črevesa Adjuvant treatment of colon cancer

Abstract

Incidenca raka debelega črevesa še vedno narašča. Odkrit v zgodnjem stadiju je ozdravljiva bolezen že s samo kirurškim posegom. Pri bolnikih stadija I in večini stadija II je operacija dovolj ter ne potrebujejo dodatnega zdravljenja. Bolniki stadija III potrebujejo dodatno zdravljenje z adjuvantno kemoterapijo, saj ta zmanjša število ponovitev bolezni in s tem podaljša celotno preživetje ter vodi k večjemu številu ozdravljenih bolnikov. Glede na rezultate nedavnih raziskav pa tudi bolnikom stadija II glede na prisotnost rizičnih dejavnikov priporočamo zdravljenje z adjuvantno kemoterapijo.

Abstract (Eng)

The incidence of colon cancer is still increasing. If detected at an early stage, it is already curable by surgery alone. In patients with stage I disease and in the majority of patients with stage II disease, surgery is sufficient, and no additional treatment is required. However, stage III patients require additional treatment with adjuvant chemotherapy, as the latter reduces the number of disease recurrences, thus prolonging the overall survival and leading to a larger number of cured patients. Considering the results of the recent studies, stage II patients are also recommended to undergo adjuvant chemotherapy, depending on the presence of risk factors.