Citopatološka diagnostika limfomov iz vzorcev bezgavk Cytopathological diagnostics of lymphomas from lymph nodes biopsies

Abstract

S citopatološko preiskavo lahko hitro, poceni in zanesljivo diagnosticiramo bolezni bezgavk. Pogosto lahko že z mikroskopskim pregledom ugotovimo, ali gre za reaktivni limfadenitis, vnetje, zasevek ali limfom. Kadar to ni mogoče, si pomagamo z dodatnimi imunocitokemičnimi preiskavami in imunofenotipizacijo s pretočnim citometrom. V citopatološki diagnostiki limfomov uporabljamo predvsem imunofenotipizacijo s pretočnim citometrom, ker nam omogoča, da zanesljivo ločimo med reaktivnim limfadenitisom in limfomom. Hkrati pa nam v večini primerov pomaga klasificirati limfom.

Abstract (Eng)

Cytology examination is a rapid, low-cost and reliable method in diagnosing lymphatic diseases. In many cases, microscopic examination allows us to distinguish between reactive lymphadenitis, inflammation, metastatic disease and lymphoma. Where this is not feasible, additional techniques, i.e. immunocytochemistry and flow cytometric immunophenotyping, are used. In cytopathological diagnostics of lymphomas, flow cytometeic immunophenotyping is the most frequently used because it allows a reliable distinction between reactive lymphadenitis and lymphoma and, in addition, it is also most helpful in classifying lymphomas.